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Open Access Anti-cancer effect of afatinib, dual inhibitor of HER2 and EGFR, on novel mutation HER2 E401G in models of patient-derived cancer

Medicine and Health

Open Access Anti-cancer effect of afatinib, dual inhibitor of HER2 and EGFR, on novel mutation HER2 E401G in models of patient-derived cancer

Y. Harada, A. Sato, et al.

This cutting-edge research by Yohei Harada and colleagues reveals the remarkable efficacy of afatinib, a dual inhibitor of HER2 and EGFR, against cancer models featuring the HER2 E401G mutation. Afatinib significantly outperformed traditional treatments, hinting at its potential as a game-changer for patients with this specific mutation.

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