Medicine and Health

NIR light-activated nanocomposites combat biofilm formation and enhance antibacterial efficacy for improved wound healing

I. Ullah, S. S. Khan, et al.

Discover the groundbreaking capabilities of selenium-tellurium doped copper oxide nanoparticles (SeTe-CuO NPs) in combating bacterial infections, showcasing remarkable antibacterial activity and accelerated wound healing when activated by near-infrared (NIR) irradiation. This innovative research was conducted by authors from various prestigious institutions.

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Abstract

This study introduces selenium-tellurium doped copper oxide nanoparticles (SeTe-CuO NPs) with photodynamic and photothermal properties for combating bacterial infections. In vitro tests showed significant antibacterial activity and biofilm inhibition under near-infrared (NIR) irradiation. In vivo studies demonstrated accelerated wound closure and bacterial clearance in wounds treated with NIR-activated SeTe-CuO NPs. This versatile platform shows promise for treating multidrug-resistant bacteria and improving wound care.

Publisher

Communications Chemistry

Published On

Jun 08, 2024

Authors

Irfan Ullah, Shahin Shah Khan, Waqar Ahmad, Luo Liu, Ahmed Rady, Badr Aldahmash, Yingjie Yu, Jian Wang, Yushu Wang

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