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Multivariate analyses of immune markers reveal increases in plasma EN-RAGE in first-episode psychosis patients

Medicine and Health

Multivariate analyses of immune markers reveal increases in plasma EN-RAGE in first-episode psychosis patients

L. Korhonen, E. R. Paul, et al.

This innovative study conducted by Laura Korhonen and colleagues explores plasma proteins in drug-naive first-episode psychosis patients compared to healthy controls. By analyzing 92 immune markers, the research identifies 11 key proteins, revealing significant increases in pro-inflammatory proteins such as interleukin-6 and EN-RAGE, which may play crucial roles in the early stages of acute psychosis.

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