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Multiplexed histology analyses for the phenotypic and spatial characterization of human innate lymphoid cells

Biology

Multiplexed histology analyses for the phenotypic and spatial characterization of human innate lymphoid cells

A. Pascual-reguant, R. Köhler, et al.

This study by Anna Pascual-Reguant and colleagues unveils the intricate world of innate lymphoid cells (ILCs), exploring their localization and interactions within the tonsil microenvironment. By identifying IRF4 as a specific marker for tonsillar ILC3s, the researchers reveal shared niches with plasma cells, paving the way for deeper understanding of ILC biology through advanced histological techniques.

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