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Mapping disease regulatory circuits at cell-type resolution from single-cell multiomics data

Medicine and Health

Mapping disease regulatory circuits at cell-type resolution from single-cell multiomics data

X. Chen, Y. Wang, et al.

Discover the innovative MAGICAL framework, developed by researchers including Xi Chen and Vance G. Fowler Jr, which accurately maps disease-associated regulatory circuits using cutting-edge genomic techniques. This groundbreaking approach helped reveal epigenetic biomarkers that differentiate between methicillin-resistant and methicillin-susceptible *Staphylococcus aureus* infections, providing crucial insights into sepsis from patient samples.

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