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Long-term neurologic outcomes of COVID-19

Medicine and Health

Long-term neurologic outcomes of COVID-19

E. Xu, Y. Xie, et al.

This groundbreaking study, conducted by Evan Xu, Yan Xie, and Ziyad Al-Aly, uncovers the alarming long-term neurologic effects of COVID-19. With over 154,000 individuals analyzed, researchers found a significant increase in neurologic sequelae, including strokes and cognitive disorders, even months after infection. Discover the implications of this critical research today.

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Playback language: English
Abstract
This study investigates the long-term neurologic consequences of COVID-19 using the US Department of Veterans Affairs national healthcare databases. A cohort of 154,068 individuals with COVID-19 was compared to contemporary and historical controls. Inverse probability weighting was used to balance the cohorts. Results showed an increased risk of various neurologic sequelae, including stroke, cognitive and memory disorders, peripheral nervous system disorders, and mental health disorders, persisting up to 12 months post-infection. The hazard ratio for any neurologic sequela was 1.42, with a burden of 70.69 per 1,000 persons at 12 months. Elevated risks were observed even in non-hospitalized individuals. Limitations include the predominantly White male cohort.
Publisher
Nature Medicine
Published On
Sep 22, 2022
Authors
Evan Xu, Yan Xie, Ziyad Al-Aly
Tags
COVID-19
neurologic consequences
stroke
cognitive disorders
mental health
long-term effects
healthcare databases

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