Medicine and Health

Inflammation as a diagnostic criterion in the GLIM definition of malnutrition—what CRP-threshold relates to reduced food intake in older patients with acute disease?

M. Pourhassan, T. Cederholm, et al.

This research investigates the critical serum C-reactive protein (CRP) level that increases the risk of low food intake in acutely ill older patients. The findings indicate that a CRP level of 3.0 mg/dl is a key threshold marking significant nutritional challenges, making this study essential for understanding malnutrition in clinical settings. Conducted by esteemed researchers including Maryam Pourhassan and Tommy Cederholm.

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Abstract

This study aimed to determine the serum C-reactive protein (CRP) level at which the risk of low food intake increases in acutely ill older hospitalized patients. 377 patients were analyzed, with nutritional intake determined using the food intake item of Nutritional Risk Screening and the plate diagram method. Patients with food intake <50% of requirements had significantly higher median CRP levels (P < 0.001). A serum-CRP of 3.0 mg/dl appears to be a reasonable threshold for acute inflammation leading to reduced food intake in acutely ill older patients, relevant to the GLIM malnutrition diagnosis.

Publisher

European Journal of Clinical Nutrition

Published On

Jul 19, 2021

Authors

Maryam Pourhassan, Tommy Cederholm, Ulrike Trampisch, Dorothee Volkert, Rainer Wirth

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