Identification of loci involved in childhood visual acuity and | ResearchBunny

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Abstract

This study investigated the genetic and behavioral associations between childhood visual acuity, cognitive skills, and educational attainment. Researchers examined a longitudinal cohort of British children (ALSPAC, n=6807) and performed a genome-wide association study (GWAS, n=5571) on visual acuity. Results showed a positive association between visual acuity and cognitive performance, school grades, and a higher polygenic score for educational attainment (EA). A GWAS revealed associations at the NPLOC4 locus and other genes involved in sensory function. The findings suggest a complex interplay between genetics and environment in shaping visual acuity and its relationship with educational outcomes.

Publisher

npj Science of Learning

Published On

Jul 25, 2023

Authors

Judith Schmitz, Filippo Abbondanza, Krzysztof Marianski, Michelle Luciano, Silvia Paracchini

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