Medicine and Health

Identification of a new cannabidiol n-hexyl homolog in a medicinal cannabis variety with an antinociceptive activity in mice: cannabidihexol

P. Linciano, C. Citti, et al.

Discover the groundbreaking identification of cannabidihexol and Δ⁹-tetrahydrocannabihexol, new phytocannabinoids with potential analgesic properties, as reported by researchers from the University of Modena and Reggio Emilia and Mediteknology. Their research confirms the presence of these compounds in a medicinal cannabis variety, promising exciting possibilities in pain management.

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Abstract

This paper reports the identification of cannabidihexol (CBDH) and Δ⁹-tetrahydrocannabihexol (Δ⁹-THCH), new phytocannabinoids with a n-hexyl side chain on the resorcinyl moiety, in a medicinal cannabis variety. The identification was confirmed by comparing retention time, molecular ion, and fragmentation spectra with synthetic standards. CBDH showed analgesic activity in mice at low doses.

Publisher

Scientific Reports

Published On

Dec 16, 2020

Authors

Pasquale Linciano, Cinzia Citti, Fabiana Russo, Francesco Tolomeo, Aldo Laganà, Anna Laura Capriotti, Livio Luongo, Monica Iannotta, Carmela Belardo, Sabatino Maione, Flavio Forni, Maria Angela Vandelli, Giuseppe Gigli, Giuseppe Cannazza

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