This paper reports the identification of cannabidihexol (CBDH) and Δ⁹-tetrahydrocannabihexol (Δ⁹-THCH), new phytocannabinoids with a n-hexyl side chain on the resorcinyl moiety, in a medicinal cannabis variety. The identification was confirmed by comparing retention time, molecular ion, and fragmentation spectra with synthetic standards. CBDH showed analgesic activity in mice at low doses.
Publisher
Scientific Reports
Published On
Dec 16, 2020
Authors
Pasquale Linciano, Cinzia Citti, Fabiana Russo, Francesco Tolomeo, Aldo Laganà, Anna Laura Capriotti, Livio Luongo, Monica Iannotta, Carmela Belardo, Sabatino Maione, Flavio Forni, Maria Angela Vandelli, Giuseppe Gigli, Giuseppe Cannazza
Tags
cannabidihexol
Δ⁹-tetrahydrocannabihexol
phytocannabinoids
medicinal cannabis
analgesic activity
cannabis research
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