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Histones released by NETosis enhance the infectivity of SARS-CoV-2 by bridging the spike protein subunit 2 and sialic acid on host cells

Medicine and Health

Histones released by NETosis enhance the infectivity of SARS-CoV-2 by bridging the spike protein subunit 2 and sialic acid on host cells

W. Hong, J. Yang, et al.

This groundbreaking research reveals how neutrophil extracellular traps (NETs) in antiviral defense may not be what they seem. Instead of combating SARS-CoV-2, the histones released during NETosis actually boost the virus's infectivity. Conducted by a team of experts including Weiqi Hong and Jingyun Yang, this study opens new pathways for COVID-19 therapies.

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