Engineering and Technology

Highly stable integration of graphene Hall sensors on a microfluidic platform for magnetic sensing in whole blood

N. Shah, V. Iyer, et al.

This paper presents innovative CMOS-compatible graphene Hall sensors integrated with PDMS microfluidics for magnetic sensing in blood. The developed graphene micro-Hall detectors demonstrate exceptional robustness and performance, paving the way for groundbreaking clinical applications, as validated by tests with magnetic beads by authors Nishal Shah, Vasant Iyer, Zhiping Zhang, Zhaoli Gao, Juhwan Park, Venkata Yelleswarapu, Firooz Aflatouni, A. T. Charlie Johnson, and David Issadore.

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Abstract

This paper presents the development of CMOS-compatible graphene Hall sensors integrated with PDMS microfluidics for magnetic sensing in blood. These graphene micro-Hall detectors (µHDs) achieve performance comparable to the best published µHDs, demonstrate robustness in whole blood due to passivation, and enable in-flow detection of magnetic beads. The system's proof-of-concept, validated using magnetic agarose beads on a silicon substrate, showcases its potential for clinical applications with a custom CMOS chip.

Publisher

Microsystems & Nanoengineering

Published On

May 16, 2023

Authors

Nishal Shah, Vasant Iyer, Zhiping Zhang, Zhaoli Gao, Juhwan Park, Venkata Yelleswarapu, Firooz Aflatouni, A. T. Charlie Johnson, David Issadore

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