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Genomic surveillance of SARS-CoV-2 Omicron variants on a university campus

Medicine and Health

Genomic surveillance of SARS-CoV-2 Omicron variants on a university campus

A. A. Weil, K. G. Luiten, et al.

This study, conducted by a team of researchers including Ana A Weil and Kyle G Luiten, reveals how genomic surveillance on a university campus tracked the rapid surge of the SARS-CoV-2 Omicron variant, highlighting crucial differences in infection dynamics compared to Delta variants. Discover the vital role this research plays in shaping public health responses amidst the pandemic.

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Playback language: English
Abstract
This study investigated the genomic surveillance of SARS-CoV-2 Omicron variants on a university campus from September 2021 to February 2022. Whole-genome sequencing identified 209 Delta and 1,730 Omicron genomes. Omicron exhibited a shorter serial interval between infections (2 vs 6 days for Delta), a higher basic reproductive number (2.4 vs 1.8 for Delta), and a higher mean case value. Despite high vaccination rates and mitigation measures, Omicron rapidly became the dominant strain, causing a surge in cases. The study highlights the importance of genomic surveillance in informing public health responses to emerging SARS-CoV-2 variants.
Publisher
Nature Communications
Published On
Sep 06, 2022
Authors
Ana A Weil, Kyle G Luiten, Amanda M Casto, Julia C Bennett, Jessica O'Hanlon, Peter D Han, Luis S Gamboa, Evan McDermott, Melissa Truong, Geoffrey S Gottlieb, Zack Acker, Caitlin R Wolf, Ariana Magedson, Eric J Chow, Natalie K Lo, Lincoln C Pothan, Devon McDonald, Tessa C Wright, Kathryn M McCaffrey, Marlin D Figgins, Janet A Englund, Michael Boeckh, Christina M Lockwood, Deborah A Nickerson, Jay Shendure, Trevor Bedford, James P Hughes, Lea M Starita, Helen Y Chu
Tags
SARS-CoV-2
Omicron variants
genomic surveillance
Delta variant
public health
vaccination
infection dynamics

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