Medicine and HealthNature Communications
Genetically stable poliovirus vectors activate dendritic cells and prime antitumor CD8 T cell immunity
M. M. Mosaheb, E. Y. Dobrikova, et al.
This groundbreaking study by Mubeen M. Mosaheb and colleagues demonstrates the potential of the poliovirus:rhinovirus chimera, PVSRIPO, to enhance antitumor cytotoxic T lymphocyte responses. The research showcases its ability to induce effective immune responses against tumors, marking a significant step in cancer therapy.
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