logo
ResearchBunny Logo
Abstract
This research characterizes homing-based gene drives in the Mediterranean fruit fly (*Ceratitis capitata*), a significant agricultural pest. The study demonstrates the medfly's suitability for gene drive strategies, including CRISPR-Cas9 gene drive coupled with sex conversion, transforming genetic females into fertile XX males. Modeling suggests that combining sex conversion and female sterility could effectively suppress medfly populations, even with resistant alleles. The findings offer a potential environmentally friendly and economical approach to controlling medfly and related tephritid pests.
Publisher
Nature Communications
Published On
Jan 01, 2024
Authors
Angela Meccariello, Shibo Hou, Serafima Davydova, James Daniel Fawcett, Alexandra Siddall, Philip T. Leftwich, Flavia Krsticevic, Philippos Aris Papathanos, Nikolai Windbichler
Tags
Mediterranean fruit fly
gene drive
CRISPR-Cas9
sex conversion
population suppression
environmentally friendly pest control
tephritid pests

Related Publications

Explore these studies to deepen your understanding of the subject.

Dopamine release and dopamine-related gene expression in the amygdala are modulated by the gastrin-releasing peptide in opposite directions during stress-enhanced fear learning and extinction
Psychology

Dopamine release and dopamine-related gene expression in the amygdala are modulated by the gastrin-releasing peptide in opposite directions during stress-enhanced fear learning and extinction

Y. Morishita, I. Fuentes, et al.

Dopamine release and dopamine-related gene expression in the amygdala are modulated by the gastrin-releasing peptide in opposite directions during stress-enhanced fear learning and extinction
Psychology

Dopamine release and dopamine-related gene expression in the amygdala are modulated by the gastrin-releasing peptide in opposite directions during stress-enhanced fear learning and extinction

Y. Morishita, I. Fuentes, et al.

Colonial policy, ecological transformations, and agricultural “improvement”: comparing agricultural yields and expansion in the Spanish and U.S. Philippines, 1870–1925 CE
Environmental Studies and Forestry

Colonial policy, ecological transformations, and agricultural “improvement”: comparing agricultural yields and expansion in the Spanish and U.S. Philippines, 1870–1925 CE

D. M. Findley, N. Amano, et al.

Ingested nitrate and nitrite and end-stage renal disease in licensed pesticide applicators and spouses in the Agricultural Health Study
Medicine and Health

Ingested nitrate and nitrite and end-stage renal disease in licensed pesticide applicators and spouses in the Agricultural Health Study

D. Chen, C. G. Parks, et al.

Listen, Learn & Level Up
Over 10,000 hours of research content in 25+ fields, available in 12+ languages.
No more digging through PDFs—just hit play and absorb the world's latest research in your language, on your time.
listen to research audio papers with researchbunny