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Format chain exchange (FORCE) for high-throughput generation of bispecific antibodies in combinatorial binder-format matrices

Medicine and Health

Format chain exchange (FORCE) for high-throughput generation of bispecific antibodies in combinatorial binder-format matrices

S. Dengl, K. Mayer, et al.

Explore the groundbreaking research on bispecific antibodies that combines innovative formats for enhanced functionality. This study reveals the power of the Format Chain Exchange (FORCE) method, leading to the creation of diverse bsAb matrices capable of binding multiple targets simultaneously. Conducted by a team of experts including Stefan Dengl, Klaus Mayer, and others at Roche Pharma Research, this work paves the way for future advancements in antibody therapies.

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