Aggregate exposure, the combined exposures to a single chemical from all pathways, is a critical children's health issue. This paper details the development of ExpoKids, an R-based tool designed to illustrate potential differences in aggregate exposure at various childhood lifestages and the adult lifestage. ExpoKids uses oral exposure estimates generated by the US EPA's ExpoFIRST tool. The tool is applied to illustrate aggregate oral exposure for ten media, presenting average daily doses (ADD) and lifetime average daily doses (LADD) across seven postnatal childhood lifestages and adulthood. Three case examples (DEHP, manganese, and endosulfan) demonstrate ExpoKids' versatility in exploring children's health risk assessment questions by visually depicting media and lifestage contributions to aggregate exposure.

Mona Dai, Susan Y. Euling, Linda Phillips, Glenn E. Rice