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Enzymatic kinetic resolution of desmethylphosphinothricin indicates that phosphinic group is a bioisostere of carboxyl group

Biology

Enzymatic kinetic resolution of desmethylphosphinothricin indicates that phosphinic group is a bioisostere of carboxyl group

D. D. Biase, F. Cappadocio, et al.

Discover how Escherichia coli glutamate decarboxylase (EcGadB) transforms a unique phosphinic analog of glutamate into a metabolite with promising implications for prodrug design. This fascinating research was conducted by Daniela De Biase, Francesca Cappadocio, Eugenia Pennacchietti, Fabio Giovannercole, Antonio Coluccia, Jouko Vepsäläinen, and Alex Khomutov.... show more
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19
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72
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Note: The citation metrics presented here have been sourced from Semantic Scholar and OpenAlex.

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