Plastic pollution is a growing global problem. This paper presents a synthetic microbial consortium designed to efficiently upcycle polyethylene terephthalate (PET) into valuable chemicals. The consortium, composed of two *Pseudomonas putida* strains specializing in terephthalic acid (TPA) and ethylene glycol (EG) utilization, demonstrates superior performance compared to monocultures, exhibiting reduced catabolic cross-talk and faster degradation, especially at high substrate concentrations or with crude hydrolysate. The consortium also excels in producing polyhydroxyalkanoates (mcl-PHA) and *cis-cis* muconate (MA). This work highlights the potential of engineered microbial consortia for sustainable polymer upcycling.
Publisher
Nature Communications
Published On
Sep 26, 2023
Authors
Teng Bao, Yuanchao Qian, Yongping Xin, James J. Collins, Ting Lu
Tags
plastic pollution
microbial consortia
polyethylene terephthalate
upcycling
bioproducts
Pseudomonas putida
sustainability
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