Food Science and Technology

Edible mycelium as proliferation and differentiation support for anchorage-dependent animal cells in cultivated meat production

M. Ogawa, A. S. Kermani, et al.

This exciting research, conducted by Minami Ogawa and colleagues, reveals that edible microcarriers derived from fungi can significantly enhance the growth and differentiation of muscle cells for cultivated meat production. With *Aspergillus oryzae* leading the way, this study opens new avenues in biotechnology and sustainable food production.

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Playback language: English

Index

Abstract

Cultivated meat production needs bioprocess optimization to achieve high cell densities. Edible microcarriers, such as inactivated mycelium from edible fungi, offer a solution by providing a large surface area for cell adhesion and proliferation, while also integrating into the final product. This study investigated the impact of different fungal species on C2C12 myoblast and bovine satellite cell (bSC) growth and differentiation on mycelium carriers. *Aspergillus oryzae* proved most effective for cell proliferation. Both C2C12 and bSC cells differentiated on mycelium carriers, demonstrating the potential of this technology for cultivated meat production.

Publisher

npj Science of Food

Published On

Apr 30, 2024

Authors

Minami Ogawa, Alex S. Kermani, Mayrene J. Huynh, Keith Baar, J. Kent Leach, David E. Block

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