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Diversity in a dish: Leveraging organoids to reflect genetic ancestry and sex differences in health and disease

Medicine and Health

Diversity in a dish: Leveraging organoids to reflect genetic ancestry and sex differences in health and disease

F. E. A. Soussi, F. Piraino, et al.

Explore how integrating genetic ancestry and biological sex with human pluripotent stem cells and donor-specific organoids can reveal ancestry- and sex-dependent disease risks and drug responses, improving polygenic risk scores and pharmacogenomics. The review outlines scalable organoid arrays, standardization, and pooled population screens to advance equitable precision medicine. The research was conducted by Authors present in <Authors> tag.

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~3 min • Beginner • English
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