Health and Fitness

Diurnal variations of brown fat thermogenesis and fat oxidation in humans

M. Matsushita, S. Nirengi, et al.

This study by Mami Matsushita and colleagues explores the intriguing diurnal patterns of nonshivering thermogenesis (NST) in healthy humans, revealing compelling connections between brown adipose tissue activity and breakfast consumption. The findings highlight the potential implications of skipping breakfast on obesity and metabolic health.

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Playback language: English

Index

Abstract

This study examined diurnal variations of nonshivering thermogenesis (NST) in healthy humans, focusing on their relation to brown adipose tissue (BAT) activity. Forty-four healthy men underwent 18F-FDG PET and were divided into Low-BAT and High-BAT groups. Studies 1 and 2 measured energy expenditure (EE), diet-induced thermogenesis (DIT), and fat oxidation (FO) under different conditions. Results showed higher DIT and FO after breakfast in the High-BAT group. Cold-induced increases in EE, FO, and temperature differences near BAT depots were higher in the morning in the High-BAT group. This suggests higher BAT activity in the morning, potentially linking breakfast skipping with obesity and metabolic disorders.

Publisher

International Journal of Obesity

Published On

Aug 02, 2021

Authors

Mami Matsushita, Shinsuke Nirengi, Masanobu Hibi, Hitoshi Wakabayashi, Sang-il Lee, Masayuki Domichi, Naoki Sakane, Masayuki Saito

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