Biology

Disrupting cellular memory to overcome drug resistance

G. Harmange, R. A. R. Hueros, et al.

Discover the fascinating world of gene expression memory! This research, conducted by Guillaume Harmange and colleagues, unveils a novel technique called scMemorySeq that quantifies memory states in melanoma cells, revealing fluctuations that may predict therapy resistance. Notably, the study identifies key pathways influencing state switching and offers insights on overcoming treatment challenges.