This retrospective cohort study compared the effectiveness of mRNA-1273 (Moderna) and BNT162b2 (Pfizer-BioNTech) vaccines against SARS-CoV-2 infection in over 3.5 million fully vaccinated individuals. The study found that mRNA-1273 offered slightly more protection against infection than BNT162b2, reaching statistical significance at 90 days post-vaccination. However, no difference was observed in protection against hospitalization, ICU admission, or death between the two vaccines.
Publisher
Nature Communications
Published On
Nov 16, 2022
Authors
Nazmul Islam, Natalie E. Sheils, Megan S. Jarvis, Kenneth Cohen
Tags
mRNA-1273
BNT162b2
SARS-CoV-2
vaccination
effectiveness
COVID-19
comparison
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