Medicine and Health

Comparative effectiveness over time of the mRNA-1273 (Moderna) vaccine and the BNT162b2 (Pfizer-BioNTech) vaccine

N. Islam, N. E. Sheils, et al.

This study, conducted by Nazmul Islam, Natalie E. Sheils, Megan S. Jarvis, and Kenneth Cohen, reveals that the mRNA-1273 (Moderna) vaccine offers slightly more protection against SARS-CoV-2 infection compared to the BNT162b2 (Pfizer-BioNTech) vaccine, particularly at 90 days post-vaccination, although both vaccines show similar protection against severe outcomes. Dive into the findings of over 3.5 million fully vaccinated individuals!

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Abstract

This retrospective cohort study compared the effectiveness of mRNA-1273 (Moderna) and BNT162b2 (Pfizer-BioNTech) vaccines against SARS-CoV-2 infection in over 3.5 million fully vaccinated individuals. The study found that mRNA-1273 offered slightly more protection against infection than BNT162b2, reaching statistical significance at 90 days post-vaccination. However, no difference was observed in protection against hospitalization, ICU admission, or death between the two vaccines.

Publisher

Nature Communications

Published On

Nov 16, 2022

Authors

Nazmul Islam, Natalie E. Sheils, Megan S. Jarvis, Kenneth Cohen

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