Medicine and Health

Chromatin accessibility analysis identifies the transcription factor ETV5 as a suppressor of adipose tissue macrophage activation in obesity

R. Hu, W. Zhang, et al.

Discover how the activation of adipose tissue macrophages (ATMs) drives chronic inflammation and insulin resistance in obesity. This groundbreaking research, conducted by Ren-Dong Hu and colleagues, highlights the critical role of the transcription factor ETV5, whose decreased expression in ATMs from obese mice leads to macrophage activation. Explore ETV5 as a promising therapeutic target for obesity-related inflammation.

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Playback language: English

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