HumanitiesNature Communications

Cases of trisomy 21 and trisomy 18 among historic and prehistoric individuals discovered from ancient DNA

A. B. Rohrlach, M. Rivollat, et al.

In an unprecedented exploration, this study examines nearly 10,000 ancient human genomes revealing intriguing cases of trisomy. Six instances of trisomy 21 and one of trisomy 18 were identified, predominantly in infant or perinatal burials, showcasing potential societal acknowledgment of these individuals. Conducted by a collaborative team of experts, these findings shed light on early Iron Age Spain's community practices.... show more

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