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Cannabinoid CB1 receptor in dorsal telencephalic glutamatergic neurons drives overconsumption of palatable food and obesity

Medicine and Health

Cannabinoid CB1 receptor in dorsal telencephalic glutamatergic neurons drives overconsumption of palatable food and obesity

I. R. D. Azua, E. Martin-garcia, et al.

This groundbreaking study by Inigo Ruiz de Azua and colleagues sheds light on the crucial role of the cannabinoid type 1 receptor (CB1) in the brain's glutamatergic neurons. Mice genetically modified to lack CB1 in these neurons displayed significantly reduced body weight and food intake when exposed to palatable diets, revealing new insights into the mechanisms of hedonic feeding and obesity development.... show more
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Citations
13
Influential Citations
2
Reference Count
50
Citation by Year

Note: The citation metrics presented here have been sourced from Semantic Scholar and OpenAlex.

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