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BNT162b2 mRNA vaccine elicited antibody response in blood and milk of breastfeeding women

Medicine and Health

BNT162b2 mRNA vaccine elicited antibody response in blood and milk of breastfeeding women

M. Rosenberg-friedman, A. Kigel, et al.

This compelling study by Michal Rosenberg-Friedman and colleagues reveals the dynamics of vaccine-specific antibody responses in lactating women after receiving the Pfizer-BioNTech COVID-19 vaccine. Discover the rapid synchronization of antibody levels in both breast milk and serum, stabilizing two weeks post-vaccination, including potent IgG and IgA antibodies.

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Playback language: English
Abstract
This study investigates the dynamics of vaccine-specific antibody response in breast milk and serum of ten lactating women who received two doses of the Pfizer-BioNTech BNT162b2 COVID-19 mRNA vaccine. The results show a rapid and synchronized antibody response in both breast milk and serum, stabilizing 14 days after the second dose. The breast milk response includes IgG and IgA with neutralizing capacity, and levels are comparable to those elicited by the TDaP vaccine.
Publisher
Nature Communications
Published On
Oct 28, 2021
Authors
Michal Rosenberg-Friedman, Aya Kigel, Yael Bahar, Michal Werbner, Joel Alter, Yariv Yogev, Yael Dror, Ronit Lubetzky, Moshe Dessau, Meital Gal-Tanamy, Ariel Many, Yariv Wine
Tags
vaccine response
breast milk
COVID-19
mRNA vaccine
antibody levels
lactating women

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