Chemistry

Biosensing strategies for the detection of SARS-CoV-2 nucleic acids

A. Tamborelli, M. L. Mujica, et al.

Discover how a collaborative research team, including Alejandro Tamborelli and Michael López Mujica, is revolutionizing decentralized SARS-CoV-2 detection with innovative biosensors designed for rapid and accurate RNA identification. This review delves into the cutting-edge technologies shaping our response to the COVID-19 pandemic.

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~3 min • Beginner • English

Index

Abstract

The COVID-19 pandemic had devastating effects worldwide, causing a severe crisis in health systems and economies. Therefore, highly sensitive and selective analytical bioplatforms that enable decentralized and rapid detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are urgently needed. Since 2020, several reviews have covered strategies to detect SARS-CoV-2 from RNA, viral proteins, or host antibodies. In this review, we specifically address the most relevant biosensors for SARS-CoV-2 RNA detection, with special emphasis on the biorecognition layers and the different schemes for transducing the hybridization event.

Publisher

Journal of Pharmaceutical and Biomedical Analysis

Published On

Feb 28, 2023

Authors

Alejandro Tamborelli, Michael López Mujica, Pablo Gallay, Virginia Vaschetti, Daiana Reartes, Rocío Delpino, Leonardo Bravo, Soledad Bollo, Marcela Rodríguez, Dolores Rubianes, Pablo Dalmasso, Gustavo Rivas

DOI

https://doi.org/10.1016/j.jpba.2023.115370

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