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Autophagy in Cancer Progression and Therapeutics

Medicine and Health

Autophagy in Cancer Progression and Therapeutics

K. Kantserova and I. Ulasov

This groundbreaking research by K Kantserova and I Ulasov delves into the complex role of autophagy in cancer, revealing how it can hinder or aid tumor growth. Discover the dual nature of autophagy and its implications for innovative cancer therapies in this insightful review.

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Playback language: English
Abstract
This paper explores the multifaceted role of autophagy in cancer progression and its implications for cancer therapeutics. Autophagy, a catabolic process essential for cellular homeostasis, exhibits a dual nature in cancer: it can both suppress tumorigenesis in early stages and promote tumor growth in later stages by providing resistance to anticancer drugs. The review examines the impact of autophagy on various cancers and the implications for developing effective therapeutic strategies. The complex interplay between autophagy and chemotherapy is discussed, highlighting the need for a time-dependent approach to modulate autophagy for optimal therapeutic outcomes.
Publisher
Int. J. Mol. Sci
Published On
Apr 28, 2023
Authors
K Kantserova, I Ulasov
Tags
autophagy
cancer progression
tumor growth
chemotherapy
therapeutics
drug resistance
cellular homeostasis

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