Medicine and Health

Association between fatty acids and the risk of impaired glucose tolerance and type 2 diabetes mellitus in American adults: NHANES 2005–2016

X. Zhu, L. Chen, et al.

This study reveals the intriguing link between dietary fatty acids and the risk of impaired glucose tolerance and type 2 diabetes in American adults. Conducted by Xiaoqiong Zhu, Liu Chen, Jiansheng Lin, Mingqin Ba, Junqiu Liao, Ping Zhang, and Cunxi Zhao, the research uncovers how certain unsaturated fatty acids could potentially lower the risk of diabetes, providing a fresh perspective on dietary impacts on health.

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Abstract

This study investigated the association between dietary fatty acids (FAs) and the risk of impaired glucose tolerance (IGT) and type 2 diabetes mellitus (T2DM) in American adults using data from the National Health and Nutrition Examination Survey (NHANES) 2005–2016. Results showed a negative correlation between total saturated FA and IGT risk. Total FA at the fourth quintile was negatively correlated with T2DM risk compared to the first quintile. Factor analysis identified an unsaturated FA signature (including octadecenoic acid, octadecadienoic acid, octadecatrienoic acid, and eicosenoic acid) negatively associated with T2DM risk. The study suggests that several unsaturated FAs may reduce the risk of T2DM.

Publisher

Nutrition and Diabetes

Published On

May 01, 2023

Authors

Xiaoqiong Zhu, Liu Chen, Jiansheng Lin, Mingqin Ba, Junqiu Liao, Ping Zhang, Cunxi Zhao

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