This study expands the human gut microbiome reference map by combining new microbial metagenomic assembled genomes from 51,052 samples with previously published genomes. A curated set of 241,118 genomes resulted in a new reference set of 3594 high-quality species genomes, matching 83.65% of validation samples' reads. This improved reference set includes 310 novel species, highlighting the previously unknown diversity within the human gut microbiome.
Publisher
Nature Communications
Published On
Jul 05, 2022
Authors
Sigal Leviatan, Saar Shoer, Daphna Rothschild, Maria Gorodetski, Eran Segal
Tags
human gut microbiome
microbial metagenomics
reference genomes
novel species
genomic diversity
metagenomic assembled genomes
validation samples
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