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Acyl-CoA thioesterase 1 prevents cardiomyocytes from Doxorubicin-induced ferroptosis via shaping the lipid composition

Medicine and Health

Acyl-CoA thioesterase 1 prevents cardiomyocytes from Doxorubicin-induced ferroptosis via shaping the lipid composition

Y. Liu, L. Zeng, et al.

This study explores the crucial role of Acyl-CoA thioesterase 1 (Acot1) in doxorubicin-induced cardiotoxicity, shedding light on how its regulation could protect against ferroptosis in heart cells. Conducted by Yunchang Liu and colleagues, the research points to Acot1 as a promising therapeutic target for preventing damage caused by chemotherapy.

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