This study introduces a wireless, battery-free eye modulation patch for high myopia therapy. The patch, powered and controlled by external ultrasound, uses a micro-actuator to shorten axial length, microneedles to deliver riboflavin, and µ-LEDs for collagen cross-linking. In vivo experiments show significant axial length reduction (~1217 µm) and sclera strength increase (387%). This patch offers a promising approach for treating high myopia.
Publisher
Nature Communications
Published On
Feb 26, 2024
Authors
Tianyan Zhong, Hangjin Yi, Jiacheng Gou, Jie Li, Miao Liu, Xing Gao, Sizhu Chen, Hongye Guan, Shan Liang, Qianxiong He, Rui Lin, Zhihe Long, Yue Wang, Chuang Shi, Yang Zhan, Yan Zhang, Lili Xing, Jie Zhong, Xinyu Xue
Tags
high myopia
eye therapy
ultrasound
sclera strength
riboflavin delivery
micro-actuator
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