This pilot randomized controlled trial investigated the efficacy of a modified anti-inflammatory dietary pattern (IBD-MAID) designed to reduce food additives, compared to standard care, on disease activity in adults with IBD. Adults with IBD were randomized to IBD-MAID (meals provided) or general healthy eating (GHE) for 8 weeks. While no statistically significant difference was found between groups at week 8, the IBD-MAID group showed significant improvements in symptoms, quality of life, fecal calprotectin, and Crohn's disease activity. A correlation was found between reduced food additive intake and improvements in inflammatory markers and quality of life. Further research is needed to explore the effects of food additives on IBD.
