Medicine and Health

A one-two punch targeting reactive oxygen species and fibril for rescuing Alzheimer's disease

J. Wang, P. Shangguan, et al.

This groundbreaking research by Jiefei Wang and colleagues presents a novel near-infrared-II aggregation-induced emission (AIE) nanotheranostic aimed at combating Alzheimer's disease. It effectively penetrates the blood-brain barrier, binds to amyloid-beta plaques, and utilizes reactive oxygen species to mitigate plaque formation and inflammation, enhancing cognitive functions in a female AD mouse model.

00:00

Playback language: English

Related Publications

Explore these studies to deepen your understanding of the subject.

Medicine and Health

Alkaline pH Promotes NADPH Oxidase-Independent Neutrophil Extracellular Trap Formation: A Matter of Mitochondrial Reactive Oxygen Species Generation and Citrullination and Cleavage of Histone

C. N. D. Souza, L. C. D. Breda, et al.

Medicine and Health

Ultrasmall copper-based nanoparticles for reactive oxygen species scavenging and alleviation of inflammation related diseases

T. Liu, B. Xiao, et al.

Medicine and Health

A comparative study of COVID-19 transcriptional signatures between clinical samples and preclinical cell models in the search for disease master regulators and drug repositioning candidates

H. Chapola, M. A. D. Bastiani, et al.

Medicine and Health

Mediterranean diet as a strategy for preserving kidney function in patients with coronary heart disease with type 2 diabetes and obesity: a secondary analysis of CORDIOPREV randomized controlled trial

A. Podadera-herreros, A. P. A. Larriva, et al.

Listen, Learn & Level Up

Over 10,000 hours of research content in 25+ fields, available in 12+ languages.

No more digging through PDFs, just hit play and absorb the world's latest research in your language, on your time.

listen to research audio papers with researchbunny