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A CRISPR-based ultrasensitive assay detects attomolar concentrations of SARS-CoV-2 antibodies in clinical samples

Medicine and Health

A CRISPR-based ultrasensitive assay detects attomolar concentrations of SARS-CoV-2 antibodies in clinical samples

Y. Tang, T. Song, et al.

This groundbreaking research led by Yanan Tang and colleagues introduces an ultrasensitive CRISPR-based antibody detection assay for anti-SARS-CoV-2 antibodies, proving 10,000 times more sensitive than traditional methods. Its remarkable 100% sensitivity and 98.5% specificity may revolutionize antibody detection, particularly for immunocompromised individuals.

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