Medicine and Health

Virtual lesions in MEG reveal increasing vulnerability of the language network from early childhood through adolescence

B. J. Williamson, H. M. Greiner, et al.

This fascinating study explored age-related changes in the resilience of brain networks, focusing on the language network in children aged 4 to 19. Conducted by Brady J. Williamson, Hansel M. Greiner, and Darren S. Kadis, the research highlights how developmental changes in network topology contribute to increased vulnerability in brain networks as children grow.

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Abstract

This study investigates the age-related changes in the resilience of brain networks, specifically focusing on the language network, using magnetoencephalography (MEG) data from 85 children aged 4 to 19 years. By employing *in silico* attacks on brain networks, the researchers assessed network vulnerability across various densities using Functional Data Analysis (FDA). The findings reveal increased vulnerability with age for both random and betweenness centrality-based attacks on whole-brain and story networks, suggesting that developmental changes in network topology contribute to this increased vulnerability.

Publisher

Nature Communications

Published On

Nov 11, 2023

Authors

Brady J. Williamson, Hansel M. Greiner, Darren S. Kadis

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