Viral proteins resolve the virus-vector conundrum during | ResearchBunny

Index

Abstract

Hemipteran insects transmit plant viruses, activating salicylic acid (SA)-mediated antiviral defenses. This study reveals how begomoviruses and their betasatellites circumvent these defenses. The betasatellite-encoded βC1 protein inhibits SA-induced degradation of NbNPR3 (a negative regulator of SA signaling) by interacting with NbHSP90s, suppressing SA signaling. This mechanism is conserved in other aphid-borne viruses, providing insights into virus persistence strategies.

Publisher

Nature Communications

Published On

Nov 01, 2024

Authors

Jing-Ru Zhang, Yi-Ming Liu, Di Li, Yi-Jie Wu, Shi-Xing Zhao, Xiao-Wei Wang, Shu-Sheng Liu, Linda L. Walling, Li-Long Pan

Related Publications

Explore these studies to deepen your understanding of the subject.

Medicine and Health

Rosmarinic acid suppresses tau phosphorylation and cognitive decline by downregulating the JNK signaling pathway

S. Yamamoto, T. Kayama, et al.

Medicine and Health

Semen Ziziphi Spinosae attenuates blood-brain barrier dysfunction induced by lipopolysaccharide by targeting the FAK-DOCK180-Rac1-WAVE2-Arp3 signaling pathway

H. Liu, X. Zhang, et al.

Medicine and Health

Optimization of adeno-associated viral vector-mediated transduction of the corticospinal tract: comparison of four promoters

B. Nieuwenhuis, B. Haenzi, et al.

Psychology

Fear memory regulation by the cAMP signaling pathway as an index of reexperiencing symptoms in posttraumatic stress disorder

H. Hori, H. Fukushima, et al.

Listen, Learn & Level Up

Over 10,000 hours of research content in 25+ fields, available in 12+ languages.

No more digging through PDFs—just hit play and absorb the world's latest research in your language, on your time.

listen to research audio papers with researchbunny