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Vaccination of SARS-CoV-2-infected individuals expands a broad range of clonally diverse affinity-matured B cell lineages

Medicine and Health

Vaccination of SARS-CoV-2-infected individuals expands a broad range of clonally diverse affinity-matured B cell lineages

M. Chernychev, M. Sakharkar, et al.

This groundbreaking study reveals how vaccination of individuals previously infected with SARS-CoV-2 leads to intense and diverse antibody responses. Researchers isolated 459 spike-specific monoclonal antibodies, demonstrating their neutralizing ability against various viral variants, proving the efficacy of mRNA vaccines in enhancing immune response among convalescent individuals. Conducted by Mark Chernychev and colleagues.

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