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Tropane and related alkaloid skeletons via a radical [3+3]-annulation process
ChemistryCommunications Chemistry

Tropane and related alkaloid skeletons via a radical [3+3]-annulation process

E. Colson, J. Andrez, et al.

Discover a groundbreaking method for synthesizing valuable bicyclic alkaloid skeletons using visible-light photoredox catalysis. This innovative protocol, developed by Eloïse Colson and colleagues, enables high-yield and diastereoselective creation of N-arylated 8-azabicyclo[3.2.1]octane and 9-azabicyclo[3.3.1]nonane derivatives from simple starting materials.... show more
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