Medicine and Health

TREM2 in Alzheimer's Disease: From Mechanisms to Therapeutic Strategies

M. Gratuze, C. E. Leyns, et al.

This review delves into the critical role of TREM2 in late-onset Alzheimer's disease, exploring its structure, signaling pathways, and potential as a therapeutic target. The insights gathered by authors Magali Gratuze, Cecilia E.G. Leyns, and David M. Holtzman may shed light on the complex interactions involving amyloid and tau pathologies.... show more

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