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Topoisomerase 3β knockout mice show transcriptional and behavioural impairments associated with neurogenesis and synaptic plasticity

Psychology

Topoisomerase 3β knockout mice show transcriptional and behavioural impairments associated with neurogenesis and synaptic plasticity

Y. Joo, Y. Xue, et al.

Discover the pivotal role of Topoisomerase 3β (Top3β) in brain health and psychiatric disorders, as revealed by groundbreaking research from Yuyoung Joo and colleagues at the National Institute on Aging. Their studies show how Top3β knockout mice display behavioral phenotypes linked to cognitive impairments and disrupted neuronal activity. Unlock the secrets behind the neuronal functions that could lead to innovative treatments for mental health challenges.

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