Biology

Thermogenic Brown Fat in Humans: Implications in Energy Homeostasis, Obesity and Metabolic Disorders

M. Saito and Y. Okamatsu-ogura

Explore the fascinating world of human brown adipose tissue (BAT) and its vital roles in energy homeostasis and metabolic disorders. This insightful review by Masayuki Saito and Yuko Okamatsu-Ogura examines the impact of aging and sex on BAT, as well as its connections to obesity and cardiovascular diseases. Discover how BAT regulates body temperature and energy expenditure!

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Playback language: English

Index

Abstract

This review summarizes current knowledge on human brown adipose tissue (BAT), focusing on its pathophysiological roles in energy homeostasis, obesity, and related metabolic disorders. The effects of aging and sex on BAT are also discussed. BAT, through thermogenesis, plays a role in regulating body temperature, energy expenditure, and body fatness. Clinical studies reveal associations between BAT and metabolic disorders (insulin resistance, diabetes, dyslipidemia, fatty liver) and cardiovascular diseases (hypertension, atherosclerosis).

Publisher

World J Mens Health

Published On

Jul 04, 2023

Authors

Masayuki Saito, Yuko Okamatsu-Ogura

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