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The VRNetzer platform enables interactive network analysis in Virtual Reality

Biology

The VRNetzer platform enables interactive network analysis in Virtual Reality

S. Pirch, F. Müller, et al.

Unlock the potential of big data with VRNetzer, a revolutionary VR platform that facilitates the interactive exploration of large networks. Developed by noted researchers including Sebastian Pirch and Felix Müller at the CeMM Research Center for Molecular Medicine, this platform is designed to visually and analytically navigate complex systems, proving its mettle in genome-scale network exploration for rare diseases.... show more
Abstract
Networks provide a powerful representation of interacting components within complex systems, making them ideal for visually and analytically exploring big data. However, the size and complexity of many networks render static visualizations on typically-sized paper or screens impractical, resulting in proverbial ‘hairballs’. Here, we introduce a Virtual Reality (VR) platform that overcomes these limitations by facilitating the thorough visual, and interactive, exploration of large networks. Our platform allows maximal customization and extendibility, through the import of custom code for data analysis, integration of external databases, and design of arbitrary user interface elements, among other features. As a proof of concept, we show how our platform can be used to interactively explore genome-scale molecular networks to identify genes associated with rare diseases and understand how they might contribute to disease development. Our platform represents a general purpose, VR-based data exploration platform for large and diverse data types by providing an interface that facilitates the interaction between human intuition and state-of-the-art analysis methods.
Publisher
Nature Communications
Published On
Apr 23, 2021
Authors
Sebastian Pirch, Felix Müller, Eugenia Iofinova, Julia Pazmandi, Christiane V. R. Hütter, Martin Chiettini, Celine Sin, Kaan Boztug, Iana Podkosova, Hannes Kaufmann, Jörg Menche
Tags
Virtual Reality
network analysis
big data
genome-scale
molecular networks
interactive exploration
rare diseases
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