This paper investigates the origin of SARS-CoV-2, focusing on genomic data analysis to understand its notable features and potential origins. The authors conclude that SARS-CoV-2 is not a laboratory construct but likely arose through natural selection, either in an animal host before zoonotic transfer or in humans after zoonotic transfer. The possibility of selection during passage is also discussed and deemed less likely.
Publisher
Nature Medicine
Published On
Mar 17, 2020
Authors
Kristian G. Andersen, W. Ian Lipkin, Andrew Rambaut, Edward C. Holmes, Robert F. Garry
Tags
SARS-CoV-2
genomic data
natural selection
zoonotic transfer
viral origins
laboratory construct
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