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The cryo-EM structure of the bd oxidase from *M. tuberculosis* reveals a unique structural framework and enables rational drug design to combat TB

Medicine and Health

The cryo-EM structure of the bd oxidase from *M. tuberculosis* reveals a unique structural framework and enables rational drug design to combat TB

S. Safarian, H. K. Opel-reading, et al.

Explore groundbreaking research from Schara Safarian and colleagues that unveils the cryo-EM structure of cytochrome bd oxidase from Mycobacterium tuberculosis. This study reveals a novel MK-9-binding site and a unique disulfide bond, paving the way for the development of targeted drugs to combat tuberculosis and reduce drug resistance.

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