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Targeting undruggable carbohydrate recognition sites through focused fragment library design

Medicine and Health

Targeting undruggable carbohydrate recognition sites through focused fragment library design

E. Shanina, S. Kuhaudomlarp, et al.

Explore groundbreaking research that reveals metal-binding pharmacophores (MBPs) as innovative scaffolds to inhibit Ca²⁺-dependent carbohydrate-protein interactions. This pioneering study, conducted by a team of experts, highlights the specificity of these interactions and paves the way for potential drug discoveries in fighting infections by targeting key lectins.

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