Medicine and Health

Talking about diseases; developing a model of patient and public-prioritised disease phenotypes

K. Slater, P. N. Schofield, et al.

This research develops a novel phenotype model representing the public's perspective on disease using social media data, revealing 24,618 new phenotype associations. Conducted by Karin Slater, Paul N. Schofield, and their team, it highlights the importance of integrating public views to improve clinical awareness and understanding across healthcare stakeholders.

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Abstract

This research develops a phenotype model representing the public's perspective on disease using social media data and compares it to a model derived from academic phenotype databases. The social media model revealed 24,618 novel phenotype associations, 14,531 of which were statistically significant, indicating a different perspective than existing resources. Clinical review showed social media-derived associations were similarly well-established as literature-derived ones and were seen more frequently in patient clinical encounters. Integrating public perspectives can enhance clinical awareness and bridge understanding across healthcare stakeholders.

Publisher

npj Digital Medicine

Published On

Sep 30, 2024

Authors

Karin Slater, Paul N. Schofield, James Wright, Paul Clifft, Anushka Irani, William Bradlow, Furqan Aziz, Georgios V. Gkoutos

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