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Systematic characterization of cleanroom-free fabricated macrovalves, demonstrating pumps and mixers for automated fluid handling tuned for organ-on-chip applications

Engineering and Technology

Systematic characterization of cleanroom-free fabricated macrovalves, demonstrating pumps and mixers for automated fluid handling tuned for organ-on-chip applications

E. G. B. M. Bossink, A. R. Vollertsen, et al.

Integrated valves developed by Elsbeth G. B. M. Bossink and colleagues enable automated control in microfluidic systems, revolutionizing organ-on-chip applications. Their innovative mechanical macrovalve can manage large channels, achieving impressive flow rates and complete mixing in record time, while also demonstrating biocompatibility for live cell cultures.

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